Abstract: The geo-strategic location of the GCC States at the crossroads of Asia, Europe and Africa, though advantageous in many ways, exposes them to several disadvantages as well. These states are particularly vulnerable to organized crime syndicates that monopolize narcotics and human trafficking operations, the second and third largest organized crime activities after arms smuggling. The Gulf States are being used as the main transit zone for Afghan narcotics being smuggled to the West and are facing an increasing domestic drug abuse problem. In addition to this, the GCC region is exposed to the growing threat of human trafficking which affects an estimated 700,000-2,000,000 people per year as they are trafficked across state boundaries. There is a misconception that human trafficking is restricted to helpless women and children, but even men are subjected to it. Akin to modern day slavery, human trafficking also includes forced labor and sexual exploitation. Existing counter-trafficking measures, both regional and global, have several shortcomings. In view of the serious security threats posed by narcotics and human trafficking, the GCC states have taken significant measures which are expected to act as an effective deterrent. This study reviews both human and narcotics trafficking in the GCC, and assesses the measures taken at the state and regional levels. It is imperative for the leadership in these states to grasp the extent of this crisis and plan for the negative fallout they are likely to face. The GCC States need to chalk out a strategy at the regional level to address the resulting security implications.