Historically, the international relations of the European Union (EU) have been guided by the interests of its member countries and by the heritage that each of them has chosen to promote, or pass on to the Union. The colonial legacy plays a crucial role in determining and developing the foreign policy of the Union. The authors approach the relationships between the GCC and EU through analyzing the prevalent operational mechanisms in each of the two regional organizations. The great differences between them hinder the improvement of their collective relations. This renders it imperative upon all the parties concerned to clarify the reasons to facilitate further development. This research paper, however, provides in-depth analysis for the adopted mechanisms and policies by each of the two blocs and highlights the political and institutional priorities for such differences as well as it presents a workable perspective for bilateral cooperation.